Dr. John Warrick

Associate Professor of Biology
B-212 Gottwald Science Center
Office: (804) 289-8231
Fax: (804) 289-8233

Teaching:
Genetics
Neurobiology

Research:
Drosophilia models to study human polyglutamine diseases. Secondary interests include the study of neurogenetic behavior in Drosophila, especially circadian rhythms and visually driven behaviors.

Education:
Ph.D., Temple University
B.S., King's College

Selected Publications:

Boeddrich A, Gaumer S, Haacke A, Tzvetkov N, Albrecht M, Evert BO, Muller EC, Lurz R, Breuer P, Schugardt N, Plassmann S, Xu K, Warrick JM, Suopanki J, Wullner U, Frank R, Hartl UF, Bonini NM, Wanker EE. (2006). An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.  EMBO J.; 25(7):1547-58

Warrick, J.M., Gordesky-Gold, B., Morabito, L., Faust, L., Paulson, H.L., and Bonini, N.M. (2005). Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism. Mol Cell: 18, 37-48.

Chan, H.Y.E*. and Warrick, J.M.*, Andriola, I., and Merry, D., and Bonini, N.M.  (2002).  Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila. Human Molecular Genetics 11 (23):2895-2904.

Awards:

Jeffress Memorial Trust, "CREB-binding Protein Modulation in a Drosophila Model of MJD and the Role of Chaperones"

National Institutes of Health, “Finding polyglutamine disease and rescue mechanisms using proteomic analysis”